Read "Enzymes Biochemistry, Biotechnology, Clinical Chemistry" by T Palmer available from Rakuten Kobo. Sign up today and get $5 off your first download. Enzymes - 2nd Edition - ISBN: , Authors: T Palmer P L Bonner. eBook ISBN: Paperback ISBN. Enzymes: Biochemistry, Biotechnology, Clinical Chemistry T Palmer, P L Bonner. In recent years, there have T Palmer, P L Bonner for online ebook. Enzymes.
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Results 1 - 16 of 25 Enzymes: Biochemistry, Biotechnology, Clinical Chemistry (Horwood Series in Chemical Science). 1 January by Trevor Palmer. Enzymes: Biochemistry, Biotechnology, Clinical Chemistry eBook: T Palmer, P L Bonner: ipprofehaphvol.tk: site Store. TIBS 11 - March All about Enzymes Understanding Enzymes (2nd Edition) by Trevor Palmer, Ellis Horwood, £ ( pages) ISBN 0
Accordingly, it has long been my habit, on meeting a new textbook, to see how these points are dealt with.
Understanding Enzymes presents the ionic structure of amino acids and proteins in a rather puzzling way: sometimes, and indeed on the first mention, they appear in appropriate ionic states, but elsewhere, including the section in which the structures are formally described, they appear in neutral states.
The Michaelis-Menten equation is illustrated twice by rough sketches that suggest that the rate reaches the limit at about twelve times the Michaelis constant, and in this connection one cannot forbear to mention that the technical quality of some of the illustrations is among the lowest I have ever seen in a book offered by a reputable publisher.
Despite these criticisms, there is an astonishing amount of information packed into the book's pages, including a fairly thorough account of enzyme kin- etics beyond the level found in most general textbooks, and a useful account of the medical and industrial importance of enzymes.
But I hope that some day someone will explain why it is apparently not possible to discuss clinical uses of enzymes without hiding them behind names like AST, formerly known to clinical chemists as GOT. Many of the chapters are concluded with problems, which are both well thought-out and discussed in detail in the back of the book. Wills never saw his finished book; he died but a few hours before the first copies were received from the press.
Nonetheless, he has left a valuable legacy to students and teachers of medicine who are certain to appreciate his attempt to show 'the great importance and significance of the subject in medicine'. In some cases, structures and pathways are relegated to an appendix, on the premise that other texts cover such topics as protein synthesis and basic metabolic pathways. However, the appendix treatment for enzyme kinetics is quite daunting for a student with no previous experience of the subject; for example, the outline for oxidation of fatty acids is quite uninformative and confusing for such students.
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The book is ideal for students who have had an introductory course in biochemistry at the level of Stryer or Lehninger. They will seek in vain in the index for enzyme regulation, mechanisms of insulin action and gene transcription and translation.
In spite of the above limitations, this book has much to recommend it, and teachers of the subject would do well to consider seriously the syllabus it follows. With the judicious application of 'refresher' material on basic mechanisms, and addition of some clinical cases and problems to be solved, the book could be an excellent teaching manual for instructors.
On the whole, the text is clear and concise, though tending towards a somewhat telegraphic, didactic style.
It might have been enlivened by more of the topical argumentative approach of the excellent nutrition sections, and some of the currently controversial areas, such as megavitamin usage, would have added interest.
Each instructor will doubtless find some area of his own interest that he feels is neglected or distorted, but on the whole this book is a great achievement for one author, providing a quite up-to-date survey of major aspects of biochemistry that are relevant to clinical studies. For students, or medical practitioners who wish to refresh their knowledge, the presentation is eminently readable.
The sections are remarkably self-contained,. Once pure enzymes were available, their structure and properties could be determined, and the findings form the material for most of this book.
Today, enzymes still form a major subject for academic research. They are investigated in hospitals as an aid to diagnosis and, because of their specificity of action, are of great value as analytical reagents.
Enzymes are still widely used in industry, continuing and extending many processes which have been used since the dawn of history. The only major exceptions to this are the proteolytic enzymes, i.
Understanding enzymes (2nd edition)
The names of enzymes usually indicate the substrate involved. Thus, lactase catalyses the hydrolysis of the disaccharide lactose to its component monosaccharides, glucose and galactose: 1.
The former is used because it sounds better but it introduces a possible trap for the unwary because it could easily suggest an enzyme acting on the substrate lactate. There is nothing in the name of this enzyme or many others to indicate the type of reaction being catalysed.
Fumarase, for example, by analogy with lactase might be supposed to catalyse a hydrolytic reaction, but, in fact, it hydrates fumarate to form malate: 1. Some names, such as catalase, indicate neither the substrate nor the reaction catalase mediates the decomposition of hydrogen peroxide.
Needless to say, whenever a new enzyme has been characterized, great care has usually been taken not to give it exactly the same name as an enzyme catalysing a different reaction. Also, the names of many enzymes make clear the substrate and the nature of the reaction being catalysed.
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For example, there is little ambiguity about the reaction catalysed by malate dehydrogenase.Feb 27, Rohit rated it liked it Recommends it for: Continue shopping. Rivka Barkai-Golan.
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